tau-441 (K18), (P301L) Protein

Catalog No. ABIN7488876

This Recombinant protein is expressed in Escherichia coli (E. coli).

Quick Overview for tau-441 (K18), (P301L) Protein (ABIN7488876)

Target: tau-441

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: 95 %

Grade: HPLC verified

Product Details

Protein Characteristics: K18, P301L

Purpose: Human Tau-441 (K18, P301L) Protein, Tag Free (HPLC verified)

Sequence: Gln 244 - Glu 372

Characteristics: Human Tau-441 (K18, P301L) Protein, Tag Free is expressed from E. coli cells. It contains AA Gln 244 - Glu 372 (Accession # P10636-8 (P301L).

Endotoxin Level: 0.1 EU per μg

Application Details

Comment:

This protein carries no "tag". () The protein has a calculated MW of 13.8 kDa. The protein migrates as 16-17 kDa under reducing (R) condition (SDS-PAGE).

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 50 mM Tris, 150 mM NaCl, 1 mM TCEP, 1 mM EDTA, pH 7.5

Storage: -80 °C

Storage Comment: -70°C

Target Details

Target: tau-441

Alternative Name: Tau-441 

Background: Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies.

Molecular Weight: 13.8 kDa